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Chronic loss of inhibition in piriform cortex following brief, daily optogenetic stimulation
It is well established that seizures beget seizures, yet the cellular processes that underlie progressive epileptogenesis remain unclear. Here, we use optogenetics to briefly activate targeted populations of mouse piriform cortex (PCx) principal neurons in vivo. After just 3 or 4 days of stimulation...
Autores principales: | Ryu, Brendan, Nagappan, Shivathmihai, Santos-Valencia, Fernando, Lee, Psyche, Rodriguez, Erica, Lackie, Meredith, Takatoh, Jun, Franks, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102022/ https://www.ncbi.nlm.nih.gov/pubmed/33882304 http://dx.doi.org/10.1016/j.celrep.2021.109001 |
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