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Asprosin-neutralizing antibodies as a treatment for metabolic syndrome
BACKGROUND: Recently, we discovered a new glucogenic and centrally acting orexigenic hormone – asprosin. Asprosin is elevated in metabolic syndrome (MS) patients, and its genetic loss results in reduced appetite, leanness, and blood glucose burden, leading to protection from MS. METHODS: We generate...
Autores principales: | Mishra, Ila, Duerrschmid, Clemens, Ku, Zhiqiang, He, Yang, Xie, Wei, Silva, Elizabeth Sabath, Hoffman, Jennifer, Xin, Wei, Zhang, Ningyan, Xu, Yong, An, Zhiqiang, Chopra, Atul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102062/ https://www.ncbi.nlm.nih.gov/pubmed/33904407 http://dx.doi.org/10.7554/eLife.63784 |
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