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Common virulence gene expression in adult first-time infected malaria patients and severe cases

Sequestration of Plasmodium falciparum(P. falciparum)-infected erythrocytes to host endothelium through the parasite-derived P. falciparum erythrocyte membrane protein 1 (PfEMP1) adhesion proteins is central to the development of malaria pathogenesis. PfEMP1 proteins have diversified and expanded to...

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Detalles Bibliográficos
Autores principales: Wichers, J Stephan, Tonkin-Hill, Gerry, Thye, Thorsten, Krumkamp, Ralf, Kreuels, Benno, Strauss, Jan, von Thien, Heidrun, Scholz, Judith AM, Smedegaard Hansson, Helle, Weisel Jensen, Rasmus, Turner, Louise, Lorenz, Freia-Raphaella, Schöllhorn, Anna, Bruchhaus, Iris, Tannich, Egbert, Fendel, Rolf, Otto, Thomas D, Lavstsen, Thomas, Gilberger, Tim W, Duffy, Michael F, Bachmann, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102065/
https://www.ncbi.nlm.nih.gov/pubmed/33908865
http://dx.doi.org/10.7554/eLife.69040