Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia

The prevalence and functional impact of somatic mutations in nonleukemic T cells is not well characterized, although clonal T-cell expansions are common. In immune-mediated aplastic anemia (AA), cytotoxic T-cell expansions are shown to participate in disease pathogenesis. We investigated the mutatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Lundgren, Sofie, Keränen, Mikko A. I., Kankainen, Matti, Huuhtanen, Jani, Walldin, Gunilla, Kerr, Cassandra M., Clemente, Michael, Ebeling, Freja, Rajala, Hanna, Brück, Oscar, Lähdesmäki, Harri, Hannula, Sari, Hannunen, Tiina, Ellonen, Pekka, Young, Neal S., Ogawa, Seishi, Maciejewski, Jaroslaw P., Hellström-Lindberg, Eva, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102188/
https://www.ncbi.nlm.nih.gov/pubmed/33785863
http://dx.doi.org/10.1038/s41375-021-01231-3

Ejemplares similares

Ejemplares similares