Cargando…

Single cell sequencing of human white adipose tissue identifies novel cell states in health and obesity

White adipose tissue (WAT) is an essential regulator of energy storage and systemic metabolic homeostasis. Regulatory networks consisting of immune and structural cells are necessary to maintain WAT metabolism, which can become impaired during obesity in mammals. Using single-cell transcriptomics an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hildreth, Andrew D., Ma, Feiyang, Wong, Yung Yu, Sun, Ryan, Pellegrini, Matteo, O’Sullivan, Timothy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102391/ https://www.ncbi.nlm.nih.gov/pubmed/33907320 http://dx.doi.org/10.1038/s41590-021-00922-4

Ejemplares similares

White adipose tissue browning and obesity
por: Cui, Xiao-Bing, et al.
Publicado: (2017)

NPC1 in human white adipose tissue and obesity
por: Bambace, Clara, et al.
Publicado: (2013)

The transcription factor Fli1 restricts the formation of memory precursor NK cells during viral infection
por: Riggan, Luke, et al.
Publicado: (2022)

Regulation of S100B in white adipose tissue by obesity in mice
por: Buckman, Laura B, et al.
Publicado: (2014)

ASK1 inhibits browning of white adipose tissue in obesity
por: Lucchini, Fabrizio C., et al.
Publicado: (2020)

Adipose-Tissue-Derived Mesenchymal Stem Cells Mediate PD-L1 Overexpression in the White Adipose Tissue of Obese Individuals, Resulting in T Cell Dysfunction
por: Eljaafari, Assia, et al.
Publicado: (2021)

Unraveling White Adipose Tissue Heterogeneity and Obesity by Adipose Stem/Stromal Cell Biology and 3D Culture Models
por: Baptista, Leandra S., et al.
Publicado: (2023)

Microbiota depletion promotes browning of white adipose tissue and reduces obesity
por: Suárez-Zamorano, Nicolas, et al.
Publicado: (2015)

The Crosstalk between Gut Microbiota and White Adipose Tissue Mitochondria in Obesity
por: Colangeli, Luca, et al.
Publicado: (2023)

Differences in the Inflammatory Response of White Adipose Tissue and Adipose-Derived Stem Cells
por: Taha, Sara, et al.
Publicado: (2020)

White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation
por: Hoevenaars, Femke P. M., et al.
Publicado: (2019)

Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection
por: Hildreth, Andrew D., et al.
Publicado: (2019)

Metabolic benefits of inhibition of p38α in white adipose tissue in obesity
por: Zhang, Shengjie, et al.
Publicado: (2018)

Targeting White Adipose Tissue with Exercise or Bariatric Surgery as Therapeutic Strategies in Obesity
por: Giolo De Carvalho, Flávia, et al.
Publicado: (2019)

The Effect of Silibinin on Protein Expression Profile in White Adipose Tissue of Obese Mice
por: Wang, Fei, et al.
Publicado: (2020)

Remodeling of Macrophages in White Adipose Tissue under the Conditions of Obesity as well as Lipolysis
por: Tong, Xiaohui, et al.
Publicado: (2021)

Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue
por: Caputo, Tiziana, et al.
Publicado: (2020)

White adipose tissue cells and the progression of cachexia: inflammatory pathways
por: Neves, Rodrigo X., et al.
Publicado: (2015)

The roles of T cells in obese adipose tissue inflammation
por: Wang, Qiong, et al.
Publicado: (2021)

Obesity results in adipose tissue T cell exhaustion
por: Porsche, Cara E., et al.
Publicado: (2021)

Differential screening identifies transcripts with depot-dependent expression in white adipose tissues
por: Wu, Yu, et al.
Publicado: (2008)

Feasibility of quantifying change in immune white cells in abdominal adipose tissue in response to an immune modulator in clinical obesity
por: Sattler, Fred R., et al.
Publicado: (2020)

Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue
por: Han, Xueya, et al.
Publicado: (2023)

Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells
por: Hammarstedt, Ann, et al.
Publicado: (2012)

Deciphering White Adipose Tissue Heterogeneity
por: Luong, Quyen, et al.
Publicado: (2019)

Single-cell RNA sequencing of batch Chlamydomonas cultures reveals heterogeneity in their diurnal cycle phase
por: Ma, Feiyang, et al.
Publicado: (2021)

The Effects of Exercise Training on Obesity-Induced Dysregulated Expression of Adipokines in White Adipose Tissue
por: Sakurai, Takuya, et al.
Publicado: (2013)

Effects of obesity on sGCβ(1) mediated signaling in white adipose tissue
por: Sanyal, Abhishek, et al.
Publicado: (2015)

Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity
por: Morita, Sumiyo, et al.
Publicado: (2016)

Resveratrol-Induced White Adipose Tissue Browning in Obese Mice by Remodeling Fecal Microbiota
por: Liao, Weiyao, et al.
Publicado: (2018)

Endocannabinoids Produced by White Adipose Tissue Modulate Lipolysis in Lean but Not in Obese Rodent and Human
por: Buch, Chloé, et al.
Publicado: (2021)

BAIBA Involves in Hypoxic Training Induced Browning of White Adipose Tissue in Obese Rats
por: Feng, Junpeng, et al.
Publicado: (2022)

Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning
por: Gómez-García, Iker, et al.
Publicado: (2022)

Chronic stress, epigenetics, and adipose tissue metabolism in the obese state
por: Xiao, Yang, et al.
Publicado: (2020)

Distinct T cell subsets in adipose tissue are associated with obesity
por: Haugstøyl, Martha E., et al.
Publicado: (2022)

Metformin Prevents Key Mechanisms of Obesity-Related Complications in Visceral White Adipose Tissue of Obese Pregnant Mice
por: Schmitz, Katrin, et al.
Publicado: (2022)

Emodin Improves Glucose and Lipid Metabolism Disorders in Obese Mice via Activating Brown Adipose Tissue and Inducing Browning of White Adipose Tissue
por: Cheng, Long, et al.
Publicado: (2021)

Effects of exercise and dietary intervention on muscle, adipose tissue, and blood IRISIN levels in obese male mice and their relationship with the beigeization of white adipose tissue
por: Li, Jing, et al.
Publicado: (2022)

Editorial: Adipose Tissue in Obesity and Metabolic Disease
por: Keshvari, Sahar, et al.
Publicado: (2022)

Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis
por: Li, Qing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5aac1h0tj54ap954nakoo08ta2