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Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis

The emergence of lipid membranes and embedded proteins was essential for the evolution of cells. Translocon complexes mediate cotranslational recruitment and membrane insertion of nascent proteins, but they already contain membrane-integral proteins. Therefore, a simpler mechanism must exist, enabli...

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Detalles Bibliográficos
Autores principales: Eaglesfield, Ross, Madsen, Mary Ann, Sanyal, Suparna, Reboud, Julien, Amtmann, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102411/
https://www.ncbi.nlm.nih.gov/pubmed/33997704
http://dx.doi.org/10.1016/j.isci.2021.102429