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High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand
OBJECTIVE: The present study aims to examine the association between Kratom use and serum lipid level. METHOD: This study compared the serum lipid profile of Kratom users and non-users living in Nam Phu Subdistrict, a special area that allows the traditional use of Kratom. The study subjects consist...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102425/ https://www.ncbi.nlm.nih.gov/pubmed/33997428 http://dx.doi.org/10.1016/j.heliyon.2021.e06931 |
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author | La-up, Aroon Saengow, Udomsak Aramrattana, Apinun |
author_facet | La-up, Aroon Saengow, Udomsak Aramrattana, Apinun |
author_sort | La-up, Aroon |
collection | PubMed |
description | OBJECTIVE: The present study aims to examine the association between Kratom use and serum lipid level. METHOD: This study compared the serum lipid profile of Kratom users and non-users living in Nam Phu Subdistrict, a special area that allows the traditional use of Kratom. The study subjects consisted of 581 individuals aged 18 and above. Binary logistic regression was used to determine an association between Kratom use and serum lipid level. RESULTS: The findings revealed an association between Kratom use and an elevated HDL level (≥60 mg/dL) with an adjusted OR of 1.82 (95% CI, 1.17–2.8), and an association between Kratom use and a triglyceride level <90 mg/dL with an adjusted OR of 1.75 (95% CI; 1.17–2.63). There were no associations between Kratom use and LDL as well as total cholesterol level. DISCUSSION AND CONCLUSIONS: This study provided additional evidence of Kratom use and a favorable lipid profile. Prevention of coronary heart disease or cerebrovascular disease via an improvement in the lipid profile may be a future pharmaceutical application of Kratom. |
format | Online Article Text |
id | pubmed-8102425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81024252021-05-14 High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand La-up, Aroon Saengow, Udomsak Aramrattana, Apinun Heliyon Research Article OBJECTIVE: The present study aims to examine the association between Kratom use and serum lipid level. METHOD: This study compared the serum lipid profile of Kratom users and non-users living in Nam Phu Subdistrict, a special area that allows the traditional use of Kratom. The study subjects consisted of 581 individuals aged 18 and above. Binary logistic regression was used to determine an association between Kratom use and serum lipid level. RESULTS: The findings revealed an association between Kratom use and an elevated HDL level (≥60 mg/dL) with an adjusted OR of 1.82 (95% CI, 1.17–2.8), and an association between Kratom use and a triglyceride level <90 mg/dL with an adjusted OR of 1.75 (95% CI; 1.17–2.63). There were no associations between Kratom use and LDL as well as total cholesterol level. DISCUSSION AND CONCLUSIONS: This study provided additional evidence of Kratom use and a favorable lipid profile. Prevention of coronary heart disease or cerebrovascular disease via an improvement in the lipid profile may be a future pharmaceutical application of Kratom. Elsevier 2021-04-28 /pmc/articles/PMC8102425/ /pubmed/33997428 http://dx.doi.org/10.1016/j.heliyon.2021.e06931 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article La-up, Aroon Saengow, Udomsak Aramrattana, Apinun High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title | High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title_full | High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title_fullStr | High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title_full_unstemmed | High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title_short | High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand |
title_sort | high serum high-density lipoprotein and low serum triglycerides in kratom users: a study of kratom users in thailand |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102425/ https://www.ncbi.nlm.nih.gov/pubmed/33997428 http://dx.doi.org/10.1016/j.heliyon.2021.e06931 |
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