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Hypoxia promotes erythroid differentiation through the development of progenitors and proerythroblasts

Oxygen is a critical noncellular component of the bone marrow microenvironment that plays an important role in the development of hematopoietic cell lineages. In this study, we investigated the impact of low oxygen (hypoxia) on ex vivo myeloerythroid differentiation of human cord blood-derived CD34(...

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Detalles Bibliográficos
Autores principales: Bapat, Aditi, Schippel, Natascha, Shi, Xiaojian, Jasbi, Paniz, Gu, Haiwei, Kala, Mrinalini, Sertil, Aparna, Sharma, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102433/
https://www.ncbi.nlm.nih.gov/pubmed/33675821
http://dx.doi.org/10.1016/j.exphem.2021.02.012