MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4

Modified LDL-induced inflammation and oxidative stress are involved in the pathogenesis of diabetic retinopathy. Recent studies have also shown that modified LDL activates Toll-like receptor 4 (TLR4) to mediate retinal injury. However, the mechanism by which modified LDL activates TLR4 and the poten...

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Detalles Bibliográficos
Autores principales: Chen, Huaicheng, Yan, Tao, Song, Zongming, Ying, Shilong, Wu, Beibei, Ju, Xin, Yang, Xi, Qu, Jia, Wu, Wencan, Zhang, Zongduan, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102522/
https://www.ncbi.nlm.nih.gov/pubmed/33875782
http://dx.doi.org/10.1038/s12276-021-00607-w

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