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Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss

Aging is associated with cellular senescence followed by bone loss leading to bone fragility in humans. However, the regulators associated with cellular senescence in aged bones need to be identified. Hypoxia-inducible factor (HIF)−2α regulates bone remodeling via the differentiation of osteoblasts...

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Detalles Bibliográficos
Autores principales:	Lee, Sun Young, Park, Ka Hyon, Lee, Gyuseok, Kim, Su-Jin, Song, Won-Hyun, Kwon, Seung-Hee, Koh, Jeong-Tae, Huh, Yun Hyun, Ryu, Je-Hwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102580/ https://www.ncbi.nlm.nih.gov/pubmed/33811248 http://dx.doi.org/10.1038/s12276-021-00594-y

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