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Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve

Studies have shown that melatonin (MLT) can delay ovarian aging, but the mechanism has not been fully elucidated. Here we show that granulosa cells isolated from mice follicles can synthesize MLT; the addition of MLT in ovary culture system inhibited follicle activation and growth; In vivo experimen...

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Detalles Bibliográficos
Autores principales:	Yang, Chan, Liu, Qinghua, Chen, Yingjun, Wang, Xiaodong, Ran, Zaohong, Fang, Fang, Xiong, Jiajun, Liu, Guoshi, Li, Xiang, Yang, Liguo, He, Changjiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102596/ https://www.ncbi.nlm.nih.gov/pubmed/33958705 http://dx.doi.org/10.1038/s42003-021-02042-z

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