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Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis

Inflammatory bowel diseases, such as Crohn’s Disease, are characterised by an altered blood and faecal metabolome, and changes in gut microbiome composition. Here, we present an efficient, scalable, tractable systems biology framework to mechanistically link microbial strains and faecal metabolites....

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Detalles Bibliográficos
Autores principales: Heinken, Almut, Hertel, Johannes, Thiele, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102608/
https://www.ncbi.nlm.nih.gov/pubmed/33958598
http://dx.doi.org/10.1038/s41540-021-00178-6

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