Cargando…
Canavan Disease as a Model for Gene Therapy-Mediated Myelin Repair
In recent years, the scientific and therapeutic fields for rare, genetic central nervous system (CNS) diseases such as leukodystrophies, or white matter disorders, have expanded significantly in part due to technological advancements in cellular and clinical screenings as well as remedial therapies...
Autores principales: | Lotun, Anoushka, Gessler, Dominic J., Gao, Guangping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102781/ https://www.ncbi.nlm.nih.gov/pubmed/33967698 http://dx.doi.org/10.3389/fncel.2021.661928 |
Ejemplares similares
-
Editorial: Myelin Repair: At the Crossing-Lines of Myelin Biology and Gene Therapy
por: Fröhlich, Dominik, et al.
Publicado: (2022) -
Increasing N-acetylaspartate in the Brain during Postnatal Myelination Does Not Cause the CNS Pathologies of Canavan Disease
por: Appu, Abhilash P., et al.
Publicado: (2017) -
Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation
por: Corti, Manuela, et al.
Publicado: (2023) -
Myelin Repair: From Animal Models to Humans
por: Cayre, Myriam, et al.
Publicado: (2021) -
Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice
por: Fröhlich, Dominik, et al.
Publicado: (2022)