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CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases

The continued global pandemic of coronavirus disease 2019 (COVID-19) poses a serious threat to global public health and social stability and it has become a serious global public health problem. Unfortunately, existing diagnostic and therapeutic approaches for the prevention and control of COVID-19...

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Autores principales: Ding, Ronghua, Long, Jinzhao, Yuan, Mingzhu, Jin, Yuefei, Yang, Haiyan, Chen, Mengshi, Chen, Shuaiyin, Duan, Guangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102830/
https://www.ncbi.nlm.nih.gov/pubmed/33968799
http://dx.doi.org/10.3389/fcimb.2021.639108
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author Ding, Ronghua
Long, Jinzhao
Yuan, Mingzhu
Jin, Yuefei
Yang, Haiyan
Chen, Mengshi
Chen, Shuaiyin
Duan, Guangcai
author_facet Ding, Ronghua
Long, Jinzhao
Yuan, Mingzhu
Jin, Yuefei
Yang, Haiyan
Chen, Mengshi
Chen, Shuaiyin
Duan, Guangcai
author_sort Ding, Ronghua
collection PubMed
description The continued global pandemic of coronavirus disease 2019 (COVID-19) poses a serious threat to global public health and social stability and it has become a serious global public health problem. Unfortunately, existing diagnostic and therapeutic approaches for the prevention and control of COVID-19 have many shortcomings. In recent years, the emerging CRISPR/Cas technology can complement the problems of traditional methods. Biological tools based on CRISPR/Cas systems have been widely used in biomedicine. In particular, they are advantageous in pathogen detection, clinical antiviral therapy, drug, and vaccine development. Therefore, CRISPR/Cas technology may have great potential for application in the prevention and control of COVID-19 and emerging infectious diseases in the future. This article summarizes the existing applications of CRISPR/Cas technology in infectious diseases with the aim of providing effective strategies for the prevention and control of COVID-19 and other emerging infectious diseases in the future.
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spelling pubmed-81028302021-05-08 CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases Ding, Ronghua Long, Jinzhao Yuan, Mingzhu Jin, Yuefei Yang, Haiyan Chen, Mengshi Chen, Shuaiyin Duan, Guangcai Front Cell Infect Microbiol Cellular and Infection Microbiology The continued global pandemic of coronavirus disease 2019 (COVID-19) poses a serious threat to global public health and social stability and it has become a serious global public health problem. Unfortunately, existing diagnostic and therapeutic approaches for the prevention and control of COVID-19 have many shortcomings. In recent years, the emerging CRISPR/Cas technology can complement the problems of traditional methods. Biological tools based on CRISPR/Cas systems have been widely used in biomedicine. In particular, they are advantageous in pathogen detection, clinical antiviral therapy, drug, and vaccine development. Therefore, CRISPR/Cas technology may have great potential for application in the prevention and control of COVID-19 and emerging infectious diseases in the future. This article summarizes the existing applications of CRISPR/Cas technology in infectious diseases with the aim of providing effective strategies for the prevention and control of COVID-19 and other emerging infectious diseases in the future. Frontiers Media S.A. 2021-04-23 /pmc/articles/PMC8102830/ /pubmed/33968799 http://dx.doi.org/10.3389/fcimb.2021.639108 Text en Copyright © 2021 Ding, Long, Yuan, Jin, Yang, Chen, Chen and Duan https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Ding, Ronghua
Long, Jinzhao
Yuan, Mingzhu
Jin, Yuefei
Yang, Haiyan
Chen, Mengshi
Chen, Shuaiyin
Duan, Guangcai
CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title_full CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title_fullStr CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title_full_unstemmed CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title_short CRISPR/Cas System: A Potential Technology for the Prevention and Control of COVID-19 and Emerging Infectious Diseases
title_sort crispr/cas system: a potential technology for the prevention and control of covid-19 and emerging infectious diseases
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102830/
https://www.ncbi.nlm.nih.gov/pubmed/33968799
http://dx.doi.org/10.3389/fcimb.2021.639108
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