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Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis
Chrysosporium zonatum is a soil‐dwelling fungus that rarely causes pulmonary infections, and a small number of cases have been reported to date. A 74‐year‐old man, who had previously been treated for tuberculosis, presented with symptoms of low‐grade fever, anorexia, cough, and bloody sputum. Chest...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103074/ https://www.ncbi.nlm.nih.gov/pubmed/33976892 http://dx.doi.org/10.1002/rcr2.763 |
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author | Matsuzaki, Takuya Kasai, Hajime Ikeda, Hideki Tajiri, Yuki Suzuki, Kenichi Watanabe, Akira Kamei, Katsuhiko Urushibara, Takashi |
author_facet | Matsuzaki, Takuya Kasai, Hajime Ikeda, Hideki Tajiri, Yuki Suzuki, Kenichi Watanabe, Akira Kamei, Katsuhiko Urushibara, Takashi |
author_sort | Matsuzaki, Takuya |
collection | PubMed |
description | Chrysosporium zonatum is a soil‐dwelling fungus that rarely causes pulmonary infections, and a small number of cases have been reported to date. A 74‐year‐old man, who had previously been treated for tuberculosis, presented with symptoms of low‐grade fever, anorexia, cough, and bloody sputum. Chest computed tomography (CT) showed a thick‐walled cavitary lesion in the right upper lobe, in which there was a suspected mycotic mass. Initially, the patient was suspected to have chronic aspergillosis due to positive serum anti‐Aspergillus antibodies. However, bronchoscopic culture revealed the growth of C. zonatum. Symptoms and imaging findings improved with administration of voriconazole for 18 months. Infection by C. zonatum is very rare and is difficult to differentiate from aspergillosis by clinical features. Clinicians should be aware of the possibility of coinfection with C. zonatum and Aspergillus sp. Voriconazole may be an effective treatment option. |
format | Online Article Text |
id | pubmed-8103074 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-81030742021-05-10 Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis Matsuzaki, Takuya Kasai, Hajime Ikeda, Hideki Tajiri, Yuki Suzuki, Kenichi Watanabe, Akira Kamei, Katsuhiko Urushibara, Takashi Respirol Case Rep Case Reports Chrysosporium zonatum is a soil‐dwelling fungus that rarely causes pulmonary infections, and a small number of cases have been reported to date. A 74‐year‐old man, who had previously been treated for tuberculosis, presented with symptoms of low‐grade fever, anorexia, cough, and bloody sputum. Chest computed tomography (CT) showed a thick‐walled cavitary lesion in the right upper lobe, in which there was a suspected mycotic mass. Initially, the patient was suspected to have chronic aspergillosis due to positive serum anti‐Aspergillus antibodies. However, bronchoscopic culture revealed the growth of C. zonatum. Symptoms and imaging findings improved with administration of voriconazole for 18 months. Infection by C. zonatum is very rare and is difficult to differentiate from aspergillosis by clinical features. Clinicians should be aware of the possibility of coinfection with C. zonatum and Aspergillus sp. Voriconazole may be an effective treatment option. John Wiley & Sons, Ltd 2021-05-07 /pmc/articles/PMC8103074/ /pubmed/33976892 http://dx.doi.org/10.1002/rcr2.763 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Matsuzaki, Takuya Kasai, Hajime Ikeda, Hideki Tajiri, Yuki Suzuki, Kenichi Watanabe, Akira Kamei, Katsuhiko Urushibara, Takashi Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title | Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title_full | Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title_fullStr | Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title_full_unstemmed | Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title_short | Voriconazole treatment of pulmonary mycosis caused by Chrysosporium zonatum after treatment for pulmonary tuberculosis |
title_sort | voriconazole treatment of pulmonary mycosis caused by chrysosporium zonatum after treatment for pulmonary tuberculosis |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103074/ https://www.ncbi.nlm.nih.gov/pubmed/33976892 http://dx.doi.org/10.1002/rcr2.763 |
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