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Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax
Haemothorax is an accumulation of blood in the pleural space. Retained haemothorax refers to blood that cannot be drained from the pleural cavity and is associated with an increased risk of empyema and fibrothorax often necessitating surgical evacuation. We describe our experience of using intrapleu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103075/ https://www.ncbi.nlm.nih.gov/pubmed/33976889 http://dx.doi.org/10.1002/rcr2.760 |
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author | Foo, Chuan T. Herre, Jurgen |
author_facet | Foo, Chuan T. Herre, Jurgen |
author_sort | Foo, Chuan T. |
collection | PubMed |
description | Haemothorax is an accumulation of blood in the pleural space. Retained haemothorax refers to blood that cannot be drained from the pleural cavity and is associated with an increased risk of empyema and fibrothorax often necessitating surgical evacuation. We describe our experience of using intrapleural fibrinolytic therapy in three patients with different bleeding risk and acute non‐traumatic retained haemothorax. The first was a 41‐year‐old female with disseminated Candida guilliermondii sepsis and an iatrogenic haemothorax, second was a 48‐year‐old female with transfusion‐dependent acute myeloid leukaemia and spontaneous haemothorax, and the third was a 72‐year‐old female with spontaneous haemothorax from newly diagnosed lung cancer. All patients received one to two doses of intrapleural alteplase without any bleeding complications and resolution of retained haemothorax. This case series demonstrates the successful application and safety of this approach as an alternative to surgery in a well‐resourced environment with close monitoring and ready access to blood transfusion. |
format | Online Article Text |
id | pubmed-8103075 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-81030752021-05-10 Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax Foo, Chuan T. Herre, Jurgen Respirol Case Rep Case Series Haemothorax is an accumulation of blood in the pleural space. Retained haemothorax refers to blood that cannot be drained from the pleural cavity and is associated with an increased risk of empyema and fibrothorax often necessitating surgical evacuation. We describe our experience of using intrapleural fibrinolytic therapy in three patients with different bleeding risk and acute non‐traumatic retained haemothorax. The first was a 41‐year‐old female with disseminated Candida guilliermondii sepsis and an iatrogenic haemothorax, second was a 48‐year‐old female with transfusion‐dependent acute myeloid leukaemia and spontaneous haemothorax, and the third was a 72‐year‐old female with spontaneous haemothorax from newly diagnosed lung cancer. All patients received one to two doses of intrapleural alteplase without any bleeding complications and resolution of retained haemothorax. This case series demonstrates the successful application and safety of this approach as an alternative to surgery in a well‐resourced environment with close monitoring and ready access to blood transfusion. John Wiley & Sons, Ltd 2021-05-07 /pmc/articles/PMC8103075/ /pubmed/33976889 http://dx.doi.org/10.1002/rcr2.760 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Series Foo, Chuan T. Herre, Jurgen Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title | Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title_full | Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title_fullStr | Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title_full_unstemmed | Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title_short | Intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
title_sort | intrapleural fibrinolysis in acute non‐traumatic retained haemothorax |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103075/ https://www.ncbi.nlm.nih.gov/pubmed/33976889 http://dx.doi.org/10.1002/rcr2.760 |
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