A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes

BACKGROUND AND AIMS: As a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non‐hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes. METHODS: We had s...

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Autores principales: Rafiee, Mohammad, Abbasi, Mohammad, Rafieemehr, Hassan, Mirzaeian, Amin, Barzegar, Mohieddin, Amiri, Vahid, Shahsavan, Shaghayegh, Mohammadi, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103082/
https://www.ncbi.nlm.nih.gov/pubmed/33977164
http://dx.doi.org/10.1002/hsr2.282
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author Rafiee, Mohammad
Abbasi, Mohammad
Rafieemehr, Hassan
Mirzaeian, Amin
Barzegar, Mohieddin
Amiri, Vahid
Shahsavan, Shaghayegh
Mohammadi, Mohammad Hossein
author_facet Rafiee, Mohammad
Abbasi, Mohammad
Rafieemehr, Hassan
Mirzaeian, Amin
Barzegar, Mohieddin
Amiri, Vahid
Shahsavan, Shaghayegh
Mohammadi, Mohammad Hossein
author_sort Rafiee, Mohammad
collection PubMed
description BACKGROUND AND AIMS: As a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non‐hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes. METHODS: We had searched scientific sources like Web ofScience and PubMed with a combination of keywords such as HSCT, engraftment,survival, outcomes, etc. Totally, 80 articles were included. RESULTS: Here we have reviewed the effective factors onmain outcomes of HSCT including engraftment, survival, graft versus hostdisease, and Mobilization. Also, the prediction of hematological reconstitutionand some novel suggestions leading to better outcomes are reviewed. CONCLUSION: The study will be applicable for improvedmanagement of autologous and allogeneic HSCT process to increase the procedureefficiency.
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spelling pubmed-81030822021-05-10 A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes Rafiee, Mohammad Abbasi, Mohammad Rafieemehr, Hassan Mirzaeian, Amin Barzegar, Mohieddin Amiri, Vahid Shahsavan, Shaghayegh Mohammadi, Mohammad Hossein Health Sci Rep Reviews BACKGROUND AND AIMS: As a curative procedure, hematopoietic stemcell transplantation (HSCT) is an approved treatment for many malignant orbenign hematologic and non‐hematologic diseases. There are different outcomes of HSCT, as well as several parameters influencing these outcomes. METHODS: We had searched scientific sources like Web ofScience and PubMed with a combination of keywords such as HSCT, engraftment,survival, outcomes, etc. Totally, 80 articles were included. RESULTS: Here we have reviewed the effective factors onmain outcomes of HSCT including engraftment, survival, graft versus hostdisease, and Mobilization. Also, the prediction of hematological reconstitutionand some novel suggestions leading to better outcomes are reviewed. CONCLUSION: The study will be applicable for improvedmanagement of autologous and allogeneic HSCT process to increase the procedureefficiency. John Wiley and Sons Inc. 2021-05-07 /pmc/articles/PMC8103082/ /pubmed/33977164 http://dx.doi.org/10.1002/hsr2.282 Text en © 2021 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Rafiee, Mohammad
Abbasi, Mohammad
Rafieemehr, Hassan
Mirzaeian, Amin
Barzegar, Mohieddin
Amiri, Vahid
Shahsavan, Shaghayegh
Mohammadi, Mohammad Hossein
A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title_full A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title_fullStr A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title_full_unstemmed A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title_short A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
title_sort concise review on factors influencing the hematopoietic stem cell transplantation main outcomes
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103082/
https://www.ncbi.nlm.nih.gov/pubmed/33977164
http://dx.doi.org/10.1002/hsr2.282
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