Cargando…
Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation
Pancreatic beta cells undergo compensatory proliferation in the early phase of type 2 diabetes. While pathways such as FoxM1 are involved in regulating compensatory beta cell proliferation, given the lack of therapeutics effectively targeting beta cell proliferation, other targetable pathways need t...
Autores principales: | Ma, Jian, Xing, Bowen, Cao, Yan, He, Xin, Bennett, Kate E, Tong, Chao, An, Chiying, Hojnacki, Taylor, Feng, Zijie, Deng, Sunbin, Ling, Sunbin, Xie, Gengchen, Wu, Yuan, Ren, Yue, Yu, Ming, Katona, Bryson W, Li, Hongzhe, Naji, Ali, Hua, Xianxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103087/ https://www.ncbi.nlm.nih.gov/pubmed/33821572 http://dx.doi.org/10.15252/emmm.202013524 |
Ejemplares similares
-
Menin: Expanding and dichotomous roles in cancer
por: Katona, Bryson W., et al.
Publicado: (2019) -
GLP-1 signaling suppresses menin’s transcriptional block by phosphorylation in β cells
por: Xing, Bowen, et al.
Publicado: (2019) -
Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells
por: Gurung, Buddha, et al.
Publicado: (2014) -
Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription
por: Nyul, Thomas E., et al.
Publicado: (2023) -
Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in β Cells
por: Jiang, Zongzhe, et al.
Publicado: (2019)