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APC Promoter Methylation in Gastrointestinal Cancer

The adenomatous polyposis coli (APC) gene, known as tumor suppressor gene, has the two promoters 1A and 1B. Researches on APC have usually focused on its loss-of-function variants causing familial adenomatous polyposis. Hypermethylation, however, which is one of the key epigenetic alterations of the...

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Detalles Bibliográficos
Autores principales:	Zhu, Lila, Li, Xinyu, Yuan, Ying, Dong, Caixia, Yang, Mengyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103321/ https://www.ncbi.nlm.nih.gov/pubmed/33968756 http://dx.doi.org/10.3389/fonc.2021.653222

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