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Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics

A Monte Carlo simulation in a novel approach is used for studying the problem of the outbreak and spread dynamics of the new COVID-19 pandemic in this work. In particular, our goal was to generate epidemiological data based on natural mechanism of transmission of this disease assuming random interac...

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Autores principales: Maltezos, Stavros, Georgakopoulou, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103742/
https://www.ncbi.nlm.nih.gov/pubmed/33971307
http://dx.doi.org/10.1016/j.meegid.2021.104896
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author Maltezos, Stavros
Georgakopoulou, Angelika
author_facet Maltezos, Stavros
Georgakopoulou, Angelika
author_sort Maltezos, Stavros
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description A Monte Carlo simulation in a novel approach is used for studying the problem of the outbreak and spread dynamics of the new COVID-19 pandemic in this work. In particular, our goal was to generate epidemiological data based on natural mechanism of transmission of this disease assuming random interactions of a large-finite number of individuals in very short distance ranges. In the simulation we also take into account the stochastic character of the individuals in a finite population and given densities of people. On the other hand, we include in the simulation the appropriate statistical distributions for the parameters characterizing this disease. An important outcome of our work, besides the generated epidemic curves, is the methodology of determining the effective reproductive number during the main part of the daily new cases of the epidemic. Since this quantity constitutes a fundamental parameter of the SIR-based epidemic models, we also studied how it is affected by small variations of the incubation time and the crucial distance distributions, and furthermore, by the degree of quarantine measures. In addition, we compare our qualitative results with those of selected real epidemiological data
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spelling pubmed-81037422021-05-07 Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics Maltezos, Stavros Georgakopoulou, Angelika Infect Genet Evol Research Paper A Monte Carlo simulation in a novel approach is used for studying the problem of the outbreak and spread dynamics of the new COVID-19 pandemic in this work. In particular, our goal was to generate epidemiological data based on natural mechanism of transmission of this disease assuming random interactions of a large-finite number of individuals in very short distance ranges. In the simulation we also take into account the stochastic character of the individuals in a finite population and given densities of people. On the other hand, we include in the simulation the appropriate statistical distributions for the parameters characterizing this disease. An important outcome of our work, besides the generated epidemic curves, is the methodology of determining the effective reproductive number during the main part of the daily new cases of the epidemic. Since this quantity constitutes a fundamental parameter of the SIR-based epidemic models, we also studied how it is affected by small variations of the incubation time and the crucial distance distributions, and furthermore, by the degree of quarantine measures. In addition, we compare our qualitative results with those of selected real epidemiological data Elsevier B.V. 2021-08 2021-05-07 /pmc/articles/PMC8103742/ /pubmed/33971307 http://dx.doi.org/10.1016/j.meegid.2021.104896 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Paper
Maltezos, Stavros
Georgakopoulou, Angelika
Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title_full Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title_fullStr Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title_full_unstemmed Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title_short Novel approach for Monte Carlo simulation of the new COVID-19 spread dynamics
title_sort novel approach for monte carlo simulation of the new covid-19 spread dynamics
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103742/
https://www.ncbi.nlm.nih.gov/pubmed/33971307
http://dx.doi.org/10.1016/j.meegid.2021.104896
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