Cargando…

scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing

Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline does not exist to maximize variant calling accuracy. Furthermore, molecular duplicates generated in these experiments have not been utilized to optimall...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, Gavin W., Derouet, Mathieu, Darling, Gail E., Yeung, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103760/
https://www.ncbi.nlm.nih.gov/pubmed/33962667
http://dx.doi.org/10.1186/s13059-021-02364-5