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scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing
Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline does not exist to maximize variant calling accuracy. Furthermore, molecular duplicates generated in these experiments have not been utilized to optimall...
Autores principales: | Wilson, Gavin W., Derouet, Mathieu, Darling, Gail E., Yeung, Jonathan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103760/ https://www.ncbi.nlm.nih.gov/pubmed/33962667 http://dx.doi.org/10.1186/s13059-021-02364-5 |
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