Blocking circ-CNST suppresses malignant behaviors of osteosarcoma cells and inhibits glycolysis through circ-CNST-miR-578-LDHA/PDK1 ceRNA networks

BACKGROUND: CircRNA CNST (circ-CNST) is a newly identified biomarker for prognosis of osteosarcoma (OS). However, its role in OS progression remains to be well documented. METHODS: Expression of circ-CNST, microRNA (miR)-578, lactate dehydrogenase A (LDHA), and pyruvate dehydrogenase kinase 1 (PDK1)...

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Detalles Bibliográficos
Autores principales: Hu, Rui, Chen, Shan, Yan, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103765/
https://www.ncbi.nlm.nih.gov/pubmed/33962616
http://dx.doi.org/10.1186/s13018-021-02427-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103765/
https://www.ncbi.nlm.nih.gov/pubmed/33962616
http://dx.doi.org/10.1186/s13018-021-02427-0

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