Cargando…

miRNA-193a-3p Regulates the AKT2 Pathway to Inhibit the Growth and Promote the Apoptosis of Glioma Cells by Targeting ALKBH5

Emerging evidence indicates that microRNA (miR)-193a-3p is involved in the tumor progression of various cancers. However, the biological functions and precise molecular mechanisms of miR-193a-3p in gliomas have not been well documented. Accordingly, this study focused on the tumor suppressor role an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yong, Wang, Qi, Lin, Jing, Zhang, Lei, Zhang, Chi, Chen, Huairui, Qian, Jun, Luo, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103841/ https://www.ncbi.nlm.nih.gov/pubmed/33968717 http://dx.doi.org/10.3389/fonc.2021.600451

Ejemplares similares

Rectraction: miRNA-193a-3p Regulates the AKT2 Pathway to Inhibit the Growth and Promote the Apoptosis of Glioma Cells by Targeting ALKBH5
Publicado: (2021)

MicroRNA-138 modulates glioma cell growth, apoptosis and invasion through the suppression of the AKT/mTOR signalling pathway by targeting CREB1
por: Zhang, Chi, et al.
Publicado: (2020)

The Role of Exosomal miRNAs in Glioma: Biological Function and Clinical Application
por: Aili, Yirizhati, et al.
Publicado: (2021)

Circulating miRNAs as Diagnostic and Prognostic Biomarkers in High-Grade Gliomas
por: Wu, Jianing, et al.
Publicado: (2022)

The Impact of lncRNAs and miRNAs on Apoptosis in Lung Cancer
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway
por: Tian, Ruyue, et al.
Publicado: (2020)

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer
por: Qin, Xin, et al.
Publicado: (2015)

Potential Impact of ALKBH5 and YTHDF1 on Tumor Immunity in Colon Adenocarcinoma
por: Yan, Guanyu, et al.
Publicado: (2021)

Research of the mechanism on miRNA193 in exosomes promotes cisplatin resistance in esophageal cancer cells
por: Shi, Shifeng, et al.
Publicado: (2020)

Liquid Biopsy of Extracellular Vesicle-Derived miR-193a-5p in Colorectal Cancer and Discovery of Its Tumor-Suppressor Functions
por: Wei, Rui, et al.
Publicado: (2020)

Identification and validation of signature for prognosis and immune microenvironment in gastric cancer based on m6A demethylase ALKBH5
por: Ji, Tiannan, et al.
Publicado: (2023)

N(6)-Methyladenosine Associated Silencing of miR-193b Promotes Cervical Cancer Aggressiveness by Targeting CCND1
por: Huang, Chunxian, et al.
Publicado: (2021)

MicroRNA-1269a Promotes Proliferation and Arrest of Apoptosis of Glioma Cells by Directly Targeting ATRX
por: Zhang, Yulian, et al.
Publicado: (2020)

The role of angiogenic growth factors in the immune microenvironment of glioma
por: Ge, Zhengmao, et al.
Publicado: (2023)

The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling
por: Chen, Ruo Qiao, et al.
Publicado: (2019)

RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53
por: Liu, Xiangli, et al.
Publicado: (2022)

High diagnostic value of miRNAs for NSCLC: quantitative analysis for both single and combined miRNAs in lung cancer
por: Yi, Minhan, et al.
Publicado: (2021)

Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways
por: Liu, Xihong, et al.
Publicado: (2019)

Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias
por: Issa, Hasan, et al.
Publicado: (2023)

Decorin Suppresses Invasion and EMT Phenotype of Glioma by Inducing Autophagy via c-Met/Akt/mTOR Axis
por: Jia, Yanfei, et al.
Publicado: (2021)

EZH2-miRNA Positive Feedback Promotes Tumor Growth in Ovarian Cancer
por: Liu, Ting, et al.
Publicado: (2021)

Epigenetic Regulation of miRNA Expression in Malignant Mesothelioma: miRNAs as Biomarkers of Early Diagnosis and Therapy
por: Tomasetti, Marco, et al.
Publicado: (2019)

Fucosylated exosomal miRNAs as promising biomarkers for the diagnosis of early lung adenocarcinoma
por: Chen, Xiongfeng, et al.
Publicado: (2022)

Mir-193b Regulates the Differentiation, Proliferation, and Apoptosis of Bovine Adipose Cells by Targeting the ACSS2/AKT Axis
por: Kang, Zihong, et al.
Publicado: (2020)

Breast cancer identification via modeling of peripherally circulating miRNAs
por: Cui, Xiaomeng, et al.
Publicado: (2018)

Effects of miRNA-130a on the proliferation and apoptosis of glioma cell lines
por: Lu, Ke, et al.
Publicado: (2018)

miRNA-15a regulates the proliferation and apoptosis of papillary thyroid carcinoma via regulating AKT pathway
por: Jin, Jin, et al.
Publicado: (2019)

Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway
por: Sun, Ye, et al.
Publicado: (2021)

Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway
por: Guo, Jida, et al.
Publicado: (2022)

miR-193a-3p Promotes the Invasion, Migration, and Mesenchymal Transition in Glioma through Regulating BTRC
por: Zhou, Dan-Dan, et al.
Publicado: (2021)

Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K–AKT Pathway
por: Zhang, Daoyu, et al.
Publicado: (2020)

Contribution of miRNAs in the Pathogenesis of Breast Cancer
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

MiRNA Polymorphisms and Cancer Prognosis: A Systematic Review and Meta-Analysis
por: Ding, Han-xi, et al.
Publicado: (2018)

LTe2 induces cell apoptosis in multiple myeloma by suppressing AKT phosphorylation at Thr308 and Ser473
por: Zhang, Yuanjiao, et al.
Publicado: (2023)

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
por: Cheng, Angie M., et al.
Publicado: (2005)

Corrigendum: Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway
por: Guo, Jida, et al.
Publicado: (2022)

CircPCMTD1 Acts as the Sponge of miR-224-5p to Promote Glioma Progression
por: Zheng, Si-Qi, et al.
Publicado: (2019)

Epigenetic Silencing of STAT3-Targeted miR-193a, by Constitutive Activation of JAK/STAT Signaling, Leads to Tumor Progression Through Overexpression of YWHAZ in Gastric Cancer
por: Wei, Kuo-Liang, et al.
Publicado: (2021)

The role of EBV-encoded miRNA in EBV-associated gastric cancer
por: Liu, Ting, et al.
Publicado: (2023)

Genome wide analysis of circulating miRNAs in growth hormone secreting pituitary neuroendocrine tumor patients’ plasma
por: Niedra, Helvijs, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a8qd7g97qvpkgmh0pnka40h7sq