Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017

BACKGROUND: To date, our understanding of the global aortic aneurysm (AA) burden distribution is very limited. OBJECTIVE: To assess a full view of global AA burden distribution and attributable risk factors from 1990 to 2017. METHODS: We extracted data of AA deaths, disability-adjusted life years (D...

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Autores principales: Wei, Linyan, Bu, Xiang, Wang, Xiqiang, Liu, Jing, Ma, Aiqun, Wang, Tingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103850/
https://www.ncbi.nlm.nih.gov/pubmed/34040948
http://dx.doi.org/10.5334/gh.920
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author Wei, Linyan
Bu, Xiang
Wang, Xiqiang
Liu, Jing
Ma, Aiqun
Wang, Tingzhong
author_facet Wei, Linyan
Bu, Xiang
Wang, Xiqiang
Liu, Jing
Ma, Aiqun
Wang, Tingzhong
author_sort Wei, Linyan
collection PubMed
description BACKGROUND: To date, our understanding of the global aortic aneurysm (AA) burden distribution is very limited. OBJECTIVE: To assess a full view of global AA burden distribution and attributable risk factors from 1990 to 2017. METHODS: We extracted data of AA deaths, disability-adjusted life years (DALYs), and their corresponding age-standardized rates (ASRs), in general and by age/sex from the 2017 Global Burden of Disease (GBD) study. The current AA burden distribution in 2017 and its changing trend from 1990 to 2017 were separately showed. The spatial divergence was discussed from four levels: global, five social-demographic index regions, 21 GBD regions, and 195 countries and territories. We also estimated the risk factors attributable to AA related deaths. RESULTS: Globally, the AA deaths were 167,249 with an age-standardized death rate (ASDR) of 2.19/100,000 persons in 2017, among which the elderly and the males accounted for the majority. Although reductions in ASRs were observed in developed areas, AA remained an important health issue in those relatively underdeveloped areas and might be much more important in the near future. AA may increasingly affect the elderly and the female population. Similar patterns of AA DALYs burden were noted during the study period. AA burden attributable to high blood pressure and smoking decreased globally and there were many heterogeneities in their distribution. DISCUSSION: AA maintained an incremental public health issue worldwide. The change pattern of AA burden was heterogeneous across locations, ages, and sexes and it is paramount to improve resource allocation for more effective and targeted prevention strategies. Also, prevention of tobacco consumption and blood pressure control should be emphasized.
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spelling pubmed-81038502021-05-25 Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017 Wei, Linyan Bu, Xiang Wang, Xiqiang Liu, Jing Ma, Aiqun Wang, Tingzhong Glob Heart Original Research BACKGROUND: To date, our understanding of the global aortic aneurysm (AA) burden distribution is very limited. OBJECTIVE: To assess a full view of global AA burden distribution and attributable risk factors from 1990 to 2017. METHODS: We extracted data of AA deaths, disability-adjusted life years (DALYs), and their corresponding age-standardized rates (ASRs), in general and by age/sex from the 2017 Global Burden of Disease (GBD) study. The current AA burden distribution in 2017 and its changing trend from 1990 to 2017 were separately showed. The spatial divergence was discussed from four levels: global, five social-demographic index regions, 21 GBD regions, and 195 countries and territories. We also estimated the risk factors attributable to AA related deaths. RESULTS: Globally, the AA deaths were 167,249 with an age-standardized death rate (ASDR) of 2.19/100,000 persons in 2017, among which the elderly and the males accounted for the majority. Although reductions in ASRs were observed in developed areas, AA remained an important health issue in those relatively underdeveloped areas and might be much more important in the near future. AA may increasingly affect the elderly and the female population. Similar patterns of AA DALYs burden were noted during the study period. AA burden attributable to high blood pressure and smoking decreased globally and there were many heterogeneities in their distribution. DISCUSSION: AA maintained an incremental public health issue worldwide. The change pattern of AA burden was heterogeneous across locations, ages, and sexes and it is paramount to improve resource allocation for more effective and targeted prevention strategies. Also, prevention of tobacco consumption and blood pressure control should be emphasized. Ubiquity Press 2021-05-04 /pmc/articles/PMC8103850/ /pubmed/34040948 http://dx.doi.org/10.5334/gh.920 Text en Copyright: © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Research
Wei, Linyan
Bu, Xiang
Wang, Xiqiang
Liu, Jing
Ma, Aiqun
Wang, Tingzhong
Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title_full Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title_fullStr Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title_full_unstemmed Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title_short Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017
title_sort global burden of aortic aneurysm and attributable risk factors from 1990 to 2017
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103850/
https://www.ncbi.nlm.nih.gov/pubmed/34040948
http://dx.doi.org/10.5334/gh.920
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