Personalized radioiodine therapy for thyroid cancer patients with known disease

Radioactive iodine (RAI) (131)I is a targeted therapy for patients with RAI-avid follicular cell-derived thyroid cancer. However, the responsiveness to (131)I therapy varies among thyroid cancer patients mainly owing to differential RAI uptake and RAI radiosensitivity among patients’ lesions. A pers...

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Detalles Bibliográficos
Autores principales: Jhiang, Sissy M, Cheng, Peng, Nabhan, Fadi A, Sipos, Jennifer A, Menq, Chia-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103907/
https://www.ncbi.nlm.nih.gov/pubmed/33977289
http://dx.doi.org/10.12703/r/10-36
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author Jhiang, Sissy M
Cheng, Peng
Nabhan, Fadi A
Sipos, Jennifer A
Menq, Chia-Hsiang
author_facet Jhiang, Sissy M
Cheng, Peng
Nabhan, Fadi A
Sipos, Jennifer A
Menq, Chia-Hsiang
author_sort Jhiang, Sissy M
collection PubMed
description Radioactive iodine (RAI) (131)I is a targeted therapy for patients with RAI-avid follicular cell-derived thyroid cancer. However, the responsiveness to (131)I therapy varies among thyroid cancer patients mainly owing to differential RAI uptake and RAI radiosensitivity among patients’ lesions. A personalized approach to maximize (131)I therapeutic efficacy is proposed based on recent scientific advances and future opportunities.
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spelling pubmed-81039072021-05-10 Personalized radioiodine therapy for thyroid cancer patients with known disease Jhiang, Sissy M Cheng, Peng Nabhan, Fadi A Sipos, Jennifer A Menq, Chia-Hsiang Fac Rev Review Article Radioactive iodine (RAI) (131)I is a targeted therapy for patients with RAI-avid follicular cell-derived thyroid cancer. However, the responsiveness to (131)I therapy varies among thyroid cancer patients mainly owing to differential RAI uptake and RAI radiosensitivity among patients’ lesions. A personalized approach to maximize (131)I therapeutic efficacy is proposed based on recent scientific advances and future opportunities. Faculty Opinions Ltd 2021-04-07 /pmc/articles/PMC8103907/ /pubmed/33977289 http://dx.doi.org/10.12703/r/10-36 Text en Copyright: © 2021 Jhiang SM et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Jhiang, Sissy M
Cheng, Peng
Nabhan, Fadi A
Sipos, Jennifer A
Menq, Chia-Hsiang
Personalized radioiodine therapy for thyroid cancer patients with known disease
title Personalized radioiodine therapy for thyroid cancer patients with known disease
title_full Personalized radioiodine therapy for thyroid cancer patients with known disease
title_fullStr Personalized radioiodine therapy for thyroid cancer patients with known disease
title_full_unstemmed Personalized radioiodine therapy for thyroid cancer patients with known disease
title_short Personalized radioiodine therapy for thyroid cancer patients with known disease
title_sort personalized radioiodine therapy for thyroid cancer patients with known disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103907/
https://www.ncbi.nlm.nih.gov/pubmed/33977289
http://dx.doi.org/10.12703/r/10-36
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