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Comprehensive analysis based on DNA methylation and RNA-seq reveals hypermethylation of the up-regulated WT1 gene with potential mechanisms in PAM50 subtypes of breast cancer

BACKGROUND: Breast cancer (BC), one of the most widespread cancers worldwide, caused the deaths of more than 600,000 women in 2018, accounting for about 15% of all cancer-associated deaths in women that year. In this study, we aimed to discover potential prognostic biomarkers and explore their molec...

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Detalles Bibliográficos
Autores principales: Ren, Chongyang, Tang, Xiaojiang, Lan, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103922/
https://www.ncbi.nlm.nih.gov/pubmed/33987034
http://dx.doi.org/10.7717/peerj.11377