Progesterone promotes immunomodulation and tumor development in the murine mammary gland

BACKGROUND: Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formation. Recently, we reported a link between PR and im...

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Detalles Bibliográficos
Autores principales: Werner, Lauryn R, Gibson, Katelin A, Goodman, Merit L, Helm, Dominika E, Walter, Katherine R, Holloran, Sean M, Trinca, Gloria M, Hastings, Richard C, Yang, Howard H, Hu, Ying, Wei, Junping, Lei, Gangjun, Yang, Xiao-Yi, Madan, Rashna, Molinolo, Alfredo A, Markiewicz, Mary A, Chalise, Prabhakar, Axelrod, Margaret L, Balko, Justin M, Hunter, Kent W, Hartman, Zachary C, Lange, Carol A, Hagan, Christy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103939/
https://www.ncbi.nlm.nih.gov/pubmed/33958486
http://dx.doi.org/10.1136/jitc-2020-001710

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