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The relationship between aldose reductase gene C106T polymorphism and the severity of retinopathy in Type 2 diabetic patients: A case–control study

BACKGROUND: Hyperglycemia over-activates glucose reduction to sorbitol by aldose reductase (ALR) leading to osmoregulation disruption and cellular damage that cause diabetic complications. We investigated the association of C106T polymorphism of ALR2 gene with the severity of diabetic retinopathy (D...

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Detalles Bibliográficos
Autores principales: Abu-Hassan, Diala Walid, Al-Bdour, Muawyah D., Saleh, Ibraheem, Freihat, Mona, El-Khateeb, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103958/
https://www.ncbi.nlm.nih.gov/pubmed/34084181
http://dx.doi.org/10.4103/jrms.JRMS_250_20