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Effect of Subcutaneous Anti-CD20 Antibody-Mediated B Cell Depletion on Susceptibility to Pneumocystis Infection in Mice
Prior work has shown that parenterally administered anti-CD20 (5D2) inhibits CD4(+) T cell priming in response to challenge with Pneumocystis murina and predisposes to pneumonia. In this study, we investigated the effect of subcutaneous anti-CD20 antibody and Pneumocystis infection. In mice with pri...
Autores principales: | Dai, Guixiang, Noell, Kristin, Weckbecker, Gisbert, Kolls, Jay K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103991/ https://www.ncbi.nlm.nih.gov/pubmed/33952667 http://dx.doi.org/10.1128/mSphere.01144-20 |
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