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High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways

Genetic variant landscape of coronary artery disease is dominated by noncoding variants among which many occur within putative enhancers regulating the expression levels of relevant genes. It is crucial to assign the genetic variants to their correct genes both to gain insights into perturbed functi...

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Detalles Bibliográficos
Autores principales: Åkerborg, Örjan, Spalinskas, Rapolas, Pradhananga, Sailendra, Anil, Anandashankar, Höjer, Pontus, Poujade, Flore-Anne, Folkersen, Lasse, Eriksson, Per, Sahlén, Pelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104016/
https://www.ncbi.nlm.nih.gov/pubmed/30786239
http://dx.doi.org/10.1161/CIRCGEN.118.002353