Cargando…
High-Resolution Regulatory Maps Connect Vascular Risk Variants to Disease-Related Pathways
Genetic variant landscape of coronary artery disease is dominated by noncoding variants among which many occur within putative enhancers regulating the expression levels of relevant genes. It is crucial to assign the genetic variants to their correct genes both to gain insights into perturbed functi...
Autores principales: | Åkerborg, Örjan, Spalinskas, Rapolas, Pradhananga, Sailendra, Anil, Anandashankar, Höjer, Pontus, Poujade, Flore-Anne, Folkersen, Lasse, Eriksson, Per, Sahlén, Pelin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104016/ https://www.ncbi.nlm.nih.gov/pubmed/30786239 http://dx.doi.org/10.1161/CIRCGEN.118.002353 |
Ejemplares similares
-
HiCapTools: a software suite for probe design and proximity detection for targeted chromosome conformation capture applications
por: Anil, Anandashankar, et al.
Publicado: (2018) -
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
por: Freiholtz, David, et al.
Publicado: (2023) -
A Multi-Omics Approach to Liver Diseases: Integration of Single Nuclei Transcriptomics with Proteomics and HiCap Bulk Data in Human Liver
por: Cavalli, Marco, et al.
Publicado: (2020) -
Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases
por: Cavalli, Marco, et al.
Publicado: (2019) -
Whole-genome sequencing and gene network modules predict gemcitabine/carboplatin-induced myelosuppression in non-small cell lung cancer patients
por: Björn, Niclas, et al.
Publicado: (2020)