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SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation

Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infects cells through interaction of its spike protein (SARS2-S) with angiotensin-converting enzyme 2 (ACE2) and activation by proteases, in particular transmembrane protease serine 2 (TMPRSS2). Viruses can also spread through fusi...

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Detalles Bibliográficos
Autores principales:	Hörnich, Bojan F., Großkopf, Anna K., Schlagowski, Sarah, Tenbusch, Matthias, Kleine-Weber, Hannah, Neipel, Frank, Stahl-Hennig, Christiane, Hahn, Alexander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104116/ https://www.ncbi.nlm.nih.gov/pubmed/33608407 http://dx.doi.org/10.1128/JVI.00002-21

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