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Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population

BACKGROUND: Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone. The genetic polymorphisms in the CYP2B6 gene have earlier been studie...

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Detalles Bibliográficos
Autores principales:	Ahmed, Sagheer, Khan, Saeed, Janjua, Kholood, Imran, Imran, Khan, Arif Ullah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104158/ https://www.ncbi.nlm.nih.gov/pubmed/33599403 http://dx.doi.org/10.1002/mgg3.1527

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