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Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology

Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast can...

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Detalles Bibliográficos
Autores principales: Arnautovic, Aska, Olafsson, Sigurast, Wong, Julia S., Agarwal, Shailesh, Broyles, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104197/
https://www.ncbi.nlm.nih.gov/pubmed/33977003
http://dx.doi.org/10.1097/GOX.0000000000003577
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author Arnautovic, Aska
Olafsson, Sigurast
Wong, Julia S.
Agarwal, Shailesh
Broyles, Justin M.
author_facet Arnautovic, Aska
Olafsson, Sigurast
Wong, Julia S.
Agarwal, Shailesh
Broyles, Justin M.
author_sort Arnautovic, Aska
collection PubMed
description Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast cancer treatment plan. METHODS: This overview of the literature strives to broaden the exposure of the plastic surgeon to PMRT and describe the indications, guidelines, and considerations relevant to reconstructive surgery. The primary targets and dosing considerations will also be reviewed. Finally, the short- and long-term toxicities are outlined with the goal of providing the plastic surgeon insights with which to recognize certain toxicities in the clinic during follow up and to develop the fluency to be able to talk to patients about the potential for certain toxicities. RESULTS: Generally, PMRT is safe and well tolerated. Considerations in breast reconstruction should be made on a patient-by-patient basis. Plastic surgeon familiarity with PMRT, its indications, and complications will amplify the surgeon’s ability to optimize outcomes. CONCLUSIONS: As more women undergo breast reconstruction, an increasing number of patients will have PMRT as part of their breast cancer treatment plan. By understanding the basic principles of PMRT, plastic surgeons can engage patients in conversations of shared decision-making and maximize outcomes.
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spelling pubmed-81041972021-05-10 Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology Arnautovic, Aska Olafsson, Sigurast Wong, Julia S. Agarwal, Shailesh Broyles, Justin M. Plast Reconstr Surg Glob Open Breast Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast cancer treatment plan. METHODS: This overview of the literature strives to broaden the exposure of the plastic surgeon to PMRT and describe the indications, guidelines, and considerations relevant to reconstructive surgery. The primary targets and dosing considerations will also be reviewed. Finally, the short- and long-term toxicities are outlined with the goal of providing the plastic surgeon insights with which to recognize certain toxicities in the clinic during follow up and to develop the fluency to be able to talk to patients about the potential for certain toxicities. RESULTS: Generally, PMRT is safe and well tolerated. Considerations in breast reconstruction should be made on a patient-by-patient basis. Plastic surgeon familiarity with PMRT, its indications, and complications will amplify the surgeon’s ability to optimize outcomes. CONCLUSIONS: As more women undergo breast reconstruction, an increasing number of patients will have PMRT as part of their breast cancer treatment plan. By understanding the basic principles of PMRT, plastic surgeons can engage patients in conversations of shared decision-making and maximize outcomes. Lippincott Williams & Wilkins 2021-05-06 /pmc/articles/PMC8104197/ /pubmed/33977003 http://dx.doi.org/10.1097/GOX.0000000000003577 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Breast
Arnautovic, Aska
Olafsson, Sigurast
Wong, Julia S.
Agarwal, Shailesh
Broyles, Justin M.
Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title_full Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title_fullStr Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title_full_unstemmed Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title_short Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
title_sort optimizing breast reconstruction through integration of plastic surgery and radiation oncology
topic Breast
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104197/
https://www.ncbi.nlm.nih.gov/pubmed/33977003
http://dx.doi.org/10.1097/GOX.0000000000003577
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