Cargando…
Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology
Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast can...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104197/ https://www.ncbi.nlm.nih.gov/pubmed/33977003 http://dx.doi.org/10.1097/GOX.0000000000003577 |
_version_ | 1783689441992245248 |
---|---|
author | Arnautovic, Aska Olafsson, Sigurast Wong, Julia S. Agarwal, Shailesh Broyles, Justin M. |
author_facet | Arnautovic, Aska Olafsson, Sigurast Wong, Julia S. Agarwal, Shailesh Broyles, Justin M. |
author_sort | Arnautovic, Aska |
collection | PubMed |
description | Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast cancer treatment plan. METHODS: This overview of the literature strives to broaden the exposure of the plastic surgeon to PMRT and describe the indications, guidelines, and considerations relevant to reconstructive surgery. The primary targets and dosing considerations will also be reviewed. Finally, the short- and long-term toxicities are outlined with the goal of providing the plastic surgeon insights with which to recognize certain toxicities in the clinic during follow up and to develop the fluency to be able to talk to patients about the potential for certain toxicities. RESULTS: Generally, PMRT is safe and well tolerated. Considerations in breast reconstruction should be made on a patient-by-patient basis. Plastic surgeon familiarity with PMRT, its indications, and complications will amplify the surgeon’s ability to optimize outcomes. CONCLUSIONS: As more women undergo breast reconstruction, an increasing number of patients will have PMRT as part of their breast cancer treatment plan. By understanding the basic principles of PMRT, plastic surgeons can engage patients in conversations of shared decision-making and maximize outcomes. |
format | Online Article Text |
id | pubmed-8104197 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-81041972021-05-10 Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology Arnautovic, Aska Olafsson, Sigurast Wong, Julia S. Agarwal, Shailesh Broyles, Justin M. Plast Reconstr Surg Glob Open Breast Post-mastectomy radiation therapy (PMRT) is an important adjunct to improve oncologic outcomes and survival in select breast cancer patients at increased risk for local recurrence. As recommendations for PMRT broaden, an increasing number of patients will have it included as part of their breast cancer treatment plan. METHODS: This overview of the literature strives to broaden the exposure of the plastic surgeon to PMRT and describe the indications, guidelines, and considerations relevant to reconstructive surgery. The primary targets and dosing considerations will also be reviewed. Finally, the short- and long-term toxicities are outlined with the goal of providing the plastic surgeon insights with which to recognize certain toxicities in the clinic during follow up and to develop the fluency to be able to talk to patients about the potential for certain toxicities. RESULTS: Generally, PMRT is safe and well tolerated. Considerations in breast reconstruction should be made on a patient-by-patient basis. Plastic surgeon familiarity with PMRT, its indications, and complications will amplify the surgeon’s ability to optimize outcomes. CONCLUSIONS: As more women undergo breast reconstruction, an increasing number of patients will have PMRT as part of their breast cancer treatment plan. By understanding the basic principles of PMRT, plastic surgeons can engage patients in conversations of shared decision-making and maximize outcomes. Lippincott Williams & Wilkins 2021-05-06 /pmc/articles/PMC8104197/ /pubmed/33977003 http://dx.doi.org/10.1097/GOX.0000000000003577 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Breast Arnautovic, Aska Olafsson, Sigurast Wong, Julia S. Agarwal, Shailesh Broyles, Justin M. Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title | Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title_full | Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title_fullStr | Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title_full_unstemmed | Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title_short | Optimizing Breast Reconstruction through Integration of Plastic Surgery and Radiation Oncology |
title_sort | optimizing breast reconstruction through integration of plastic surgery and radiation oncology |
topic | Breast |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104197/ https://www.ncbi.nlm.nih.gov/pubmed/33977003 http://dx.doi.org/10.1097/GOX.0000000000003577 |
work_keys_str_mv | AT arnautovicaska optimizingbreastreconstructionthroughintegrationofplasticsurgeryandradiationoncology AT olafssonsigurast optimizingbreastreconstructionthroughintegrationofplasticsurgeryandradiationoncology AT wongjulias optimizingbreastreconstructionthroughintegrationofplasticsurgeryandradiationoncology AT agarwalshailesh optimizingbreastreconstructionthroughintegrationofplasticsurgeryandradiationoncology AT broylesjustinm optimizingbreastreconstructionthroughintegrationofplasticsurgeryandradiationoncology |