Cargando…

Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients

BACKGROUND: The reperfusion therapy using primary percutaneous coronary intervention (PPCI) in ST-segment elevation myocardial infarction (STEMI) is known to give a better result than fibrinolytic therapy. The fast access to PPCI will improve hospital outcome. We believe that patient access to PPCI...

Descripción completa

Detalles Bibliográficos
Autor principal: Balghith, Mohammed Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104313/
https://www.ncbi.nlm.nih.gov/pubmed/33986923
http://dx.doi.org/10.4103/HEARTVIEWS.HEARTVIEWS_70_20
_version_ 1783689468352397312
author Balghith, Mohammed Ali
author_facet Balghith, Mohammed Ali
author_sort Balghith, Mohammed Ali
collection PubMed
description BACKGROUND: The reperfusion therapy using primary percutaneous coronary intervention (PPCI) in ST-segment elevation myocardial infarction (STEMI) is known to give a better result than fibrinolytic therapy. The fast access to PPCI will improve hospital outcome. We believe that patient access to PPCI facility would have improved due to enhanced public awareness and expanding evidenced-based health provision. METHODS: This is a single-center retrospective study to analyze and compare data for STEMI patients. Patients were transferred to our hospital during the year 2010. Group l comprised 223 patients. Group 2 comprised 288 patients. Group 2 patients were those treated between August 2014 and August 2015. We compared their demographic and baseline characteristics, patients' access to the hospital, reasons for no access, and hospital mortality for the two groups. RESULTS: Among the 288 patients in Group 2, 247 patients (85%) were males with an average age of 57 years, 49% were diabetics, 48% were hypertensive, 48% were smokers, and 27% were obese. These were not different in Group 1. In Group 2, 164 patients (57%) only had access to PPCI compared to 56% in Group 1 (P = 0.536-NS). In G2, the main reasons for no PPCI were late presentation in 47% versus 53% in Group 1; P = 0.34 NS. In Group 2, 27% were due to thrombolysis versus 17% in Group 1 (P = 0.11 NS). Hospital mortality in Group 2 was 4% in those treated with PPCI compared to 2.3% in Group 1 (P = 0.522-NS). Mortality in patients who did not receive PPCI in Group 2 was 8% compared to 11.3% in Group 1 (P = 0.49-NS). Females in Group 2 have about 3 times higher mortality. Patients treated for STEMI in the last 12 months at King Abdulaziz Cardiac Center still have relatively low access to PPCI due mainly to persistent pattern of late presentation and prior thrombolysis, which reflect apparent lack of direct access to hospitals with PPCI facilities. CONCLUSION: Comparing the two periods, there was no change in cardiology practice. The low access to PPCI was mainly due to late presentation and prior thrombolysis. Hospital mortality rate for patients treated with PPCI remained low during the two era. This seemingly relates to both lack of public awareness and health provision factors in PPCI organizations.
format Online
Article
Text
id pubmed-8104313
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-81043132021-05-12 Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients Balghith, Mohammed Ali Heart Views Original Article BACKGROUND: The reperfusion therapy using primary percutaneous coronary intervention (PPCI) in ST-segment elevation myocardial infarction (STEMI) is known to give a better result than fibrinolytic therapy. The fast access to PPCI will improve hospital outcome. We believe that patient access to PPCI facility would have improved due to enhanced public awareness and expanding evidenced-based health provision. METHODS: This is a single-center retrospective study to analyze and compare data for STEMI patients. Patients were transferred to our hospital during the year 2010. Group l comprised 223 patients. Group 2 comprised 288 patients. Group 2 patients were those treated between August 2014 and August 2015. We compared their demographic and baseline characteristics, patients' access to the hospital, reasons for no access, and hospital mortality for the two groups. RESULTS: Among the 288 patients in Group 2, 247 patients (85%) were males with an average age of 57 years, 49% were diabetics, 48% were hypertensive, 48% were smokers, and 27% were obese. These were not different in Group 1. In Group 2, 164 patients (57%) only had access to PPCI compared to 56% in Group 1 (P = 0.536-NS). In G2, the main reasons for no PPCI were late presentation in 47% versus 53% in Group 1; P = 0.34 NS. In Group 2, 27% were due to thrombolysis versus 17% in Group 1 (P = 0.11 NS). Hospital mortality in Group 2 was 4% in those treated with PPCI compared to 2.3% in Group 1 (P = 0.522-NS). Mortality in patients who did not receive PPCI in Group 2 was 8% compared to 11.3% in Group 1 (P = 0.49-NS). Females in Group 2 have about 3 times higher mortality. Patients treated for STEMI in the last 12 months at King Abdulaziz Cardiac Center still have relatively low access to PPCI due mainly to persistent pattern of late presentation and prior thrombolysis, which reflect apparent lack of direct access to hospitals with PPCI facilities. CONCLUSION: Comparing the two periods, there was no change in cardiology practice. The low access to PPCI was mainly due to late presentation and prior thrombolysis. Hospital mortality rate for patients treated with PPCI remained low during the two era. This seemingly relates to both lack of public awareness and health provision factors in PPCI organizations. Wolters Kluwer - Medknow 2020 2021-01-14 /pmc/articles/PMC8104313/ /pubmed/33986923 http://dx.doi.org/10.4103/HEARTVIEWS.HEARTVIEWS_70_20 Text en Copyright: © 2021 Heart Views https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Balghith, Mohammed Ali
Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title_full Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title_fullStr Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title_full_unstemmed Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title_short Primary Percutaneous Coronary Intervention Facility Hospitals and Easy Access Can Affect the Outcomes of ST-Segment Elevation Myocardial Infarction Patients
title_sort primary percutaneous coronary intervention facility hospitals and easy access can affect the outcomes of st-segment elevation myocardial infarction patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104313/
https://www.ncbi.nlm.nih.gov/pubmed/33986923
http://dx.doi.org/10.4103/HEARTVIEWS.HEARTVIEWS_70_20
work_keys_str_mv AT balghithmohammedali primarypercutaneouscoronaryinterventionfacilityhospitalsandeasyaccesscanaffecttheoutcomesofstsegmentelevationmyocardialinfarctionpatients