Coagulopathy in COVID-19

Hemostatic derangement is a hallmark in severe COVID-19. Markedly elevation of D-dimer and fibrinogen degradation product levels were observed in patients with severe COVID-19 higher and 71.4% of nonsurvivors met the International Society of Thrombosis and Haemostasis criteria of disseminated intrav...

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Detalles Bibliográficos
Autores principales: Lio, Ka U, Rali, Parth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104350/
https://www.ncbi.nlm.nih.gov/pubmed/33686980
http://dx.doi.org/10.4103/lungindia.lungindia_226_20
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author Lio, Ka U
Rali, Parth
author_facet Lio, Ka U
Rali, Parth
author_sort Lio, Ka U
collection PubMed
description Hemostatic derangement is a hallmark in severe COVID-19. Markedly elevation of D-dimer and fibrinogen degradation product levels were observed in patients with severe COVID-19 higher and 71.4% of nonsurvivors met the International Society of Thrombosis and Haemostasis criteria of disseminated intravascular coagulation (DIC). Although the clinical and epidemiological features of COVID-19 have been well-described, the underlying mechanism influencing disease severity remains to be elucidated. Herein, the aim of this review article is to evaluate hemostasis in the pathogenesis of COVID-19 and its role in the management of this unprecedented pandemic.
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spelling pubmed-81043502021-05-12 Coagulopathy in COVID-19 Lio, Ka U Rali, Parth Lung India Review Article Hemostatic derangement is a hallmark in severe COVID-19. Markedly elevation of D-dimer and fibrinogen degradation product levels were observed in patients with severe COVID-19 higher and 71.4% of nonsurvivors met the International Society of Thrombosis and Haemostasis criteria of disseminated intravascular coagulation (DIC). Although the clinical and epidemiological features of COVID-19 have been well-described, the underlying mechanism influencing disease severity remains to be elucidated. Herein, the aim of this review article is to evaluate hemostasis in the pathogenesis of COVID-19 and its role in the management of this unprecedented pandemic. Wolters Kluwer - Medknow 2021-03 2020-09-16 /pmc/articles/PMC8104350/ /pubmed/33686980 http://dx.doi.org/10.4103/lungindia.lungindia_226_20 Text en Copyright: © 2020 Lung India https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Lio, Ka U
Rali, Parth
Coagulopathy in COVID-19
title Coagulopathy in COVID-19
title_full Coagulopathy in COVID-19
title_fullStr Coagulopathy in COVID-19
title_full_unstemmed Coagulopathy in COVID-19
title_short Coagulopathy in COVID-19
title_sort coagulopathy in covid-19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104350/
https://www.ncbi.nlm.nih.gov/pubmed/33686980
http://dx.doi.org/10.4103/lungindia.lungindia_226_20
work_keys_str_mv AT liokau coagulopathyincovid19
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