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Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China

OBJECTIVE: Dyslipidemia is a leading risk factor for cardiovascular and cerebrovascular diseases. By collecting the blood lipid profiles among adult residents of Shenmu City in Shaanxi Province, China, we aim to assess and elucidate the prevalence and risk factors of dyslipidemia in this city. METHO...

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Autores principales: Gao, Huiping, Wang, Haiying, Shan, Guangliang, Liu, Rui, Chen, Haiyuan, Sun, Shengli, Liu, Yonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104371/
https://www.ncbi.nlm.nih.gov/pubmed/33961634
http://dx.doi.org/10.1371/journal.pone.0250573
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author Gao, Huiping
Wang, Haiying
Shan, Guangliang
Liu, Rui
Chen, Haiyuan
Sun, Shengli
Liu, Yonglin
author_facet Gao, Huiping
Wang, Haiying
Shan, Guangliang
Liu, Rui
Chen, Haiyuan
Sun, Shengli
Liu, Yonglin
author_sort Gao, Huiping
collection PubMed
description OBJECTIVE: Dyslipidemia is a leading risk factor for cardiovascular and cerebrovascular diseases. By collecting the blood lipid profiles among adult residents of Shenmu City in Shaanxi Province, China, we aim to assess and elucidate the prevalence and risk factors of dyslipidemia in this city. METHOD: Stratified multistage sampling was used to survey 4,598 permanent adult residents in five areas of Shenmu (2 communities in the county seat, 2 in the southern area and 2 in the northern area) from September 2019 to December 2019. Questionnaire surveys and physical examinations were conducted. Data were analyzed using SPSS software version 26.0. RESULTS: The average level of total cholesterol (TC) is 4.47mmol/L, that of triglyceride (TG) 1.32mmol/L, high-density lipoprotein cholesterol (HDL-C) 1.27mmol/L, apolipoprotein A1 (ApoA1) 1.44g/L, low-density lipoprotein cholesterol (LDL-C) 2.7mmol/L and apolipoprotein B (ApoB) 0.97g/L. The prevalence of hypercholesterolemia (HTC), hypertriglyceridemia (HTG), low high-density lipoprotein (HDL-C) and high low-density lipoprotein (LDL-C) is 22.4%, 33.3%, 14.5%, and 5.81%, respectively, and the overall prevalence of dyslipidemia is 48.27%. Furthermore, blood lipid levels and prevalence of dyslipidemia vary by region, age, gender, occupation and educational level. Nine risk factors of dyslipidemia were identified, which are living in county seat or northern industrial area, increasing age, male, overweight or obesity, abdominal obesity, smoking, hypertension, abnormal glucose metabolism (pre-diabetes or diabetes) and hyperuricemia. CONCLUSION: The blood lipid levels and dyslipidemia prevalence of adults in Shenmu City are higher comparing to national averages of China. Combining risk factors of dyslipidemia, early detection and public health interventions are necessary in high-risk population for associated cardiovascular and cerebrovascular diseases prevention.
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spelling pubmed-81043712021-05-18 Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China Gao, Huiping Wang, Haiying Shan, Guangliang Liu, Rui Chen, Haiyuan Sun, Shengli Liu, Yonglin PLoS One Research Article OBJECTIVE: Dyslipidemia is a leading risk factor for cardiovascular and cerebrovascular diseases. By collecting the blood lipid profiles among adult residents of Shenmu City in Shaanxi Province, China, we aim to assess and elucidate the prevalence and risk factors of dyslipidemia in this city. METHOD: Stratified multistage sampling was used to survey 4,598 permanent adult residents in five areas of Shenmu (2 communities in the county seat, 2 in the southern area and 2 in the northern area) from September 2019 to December 2019. Questionnaire surveys and physical examinations were conducted. Data were analyzed using SPSS software version 26.0. RESULTS: The average level of total cholesterol (TC) is 4.47mmol/L, that of triglyceride (TG) 1.32mmol/L, high-density lipoprotein cholesterol (HDL-C) 1.27mmol/L, apolipoprotein A1 (ApoA1) 1.44g/L, low-density lipoprotein cholesterol (LDL-C) 2.7mmol/L and apolipoprotein B (ApoB) 0.97g/L. The prevalence of hypercholesterolemia (HTC), hypertriglyceridemia (HTG), low high-density lipoprotein (HDL-C) and high low-density lipoprotein (LDL-C) is 22.4%, 33.3%, 14.5%, and 5.81%, respectively, and the overall prevalence of dyslipidemia is 48.27%. Furthermore, blood lipid levels and prevalence of dyslipidemia vary by region, age, gender, occupation and educational level. Nine risk factors of dyslipidemia were identified, which are living in county seat or northern industrial area, increasing age, male, overweight or obesity, abdominal obesity, smoking, hypertension, abnormal glucose metabolism (pre-diabetes or diabetes) and hyperuricemia. CONCLUSION: The blood lipid levels and dyslipidemia prevalence of adults in Shenmu City are higher comparing to national averages of China. Combining risk factors of dyslipidemia, early detection and public health interventions are necessary in high-risk population for associated cardiovascular and cerebrovascular diseases prevention. Public Library of Science 2021-05-07 /pmc/articles/PMC8104371/ /pubmed/33961634 http://dx.doi.org/10.1371/journal.pone.0250573 Text en © 2021 Gao et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Gao, Huiping
Wang, Haiying
Shan, Guangliang
Liu, Rui
Chen, Haiyuan
Sun, Shengli
Liu, Yonglin
Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title_full Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title_fullStr Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title_full_unstemmed Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title_short Prevalence of dyslipidemia and associated risk factors among adult residents of Shenmu City, China
title_sort prevalence of dyslipidemia and associated risk factors among adult residents of shenmu city, china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104371/
https://www.ncbi.nlm.nih.gov/pubmed/33961634
http://dx.doi.org/10.1371/journal.pone.0250573
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