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HMGCR inhibition stabilizes the glycolytic enzyme PKM2 to support the growth of renal cell carcinoma
Renal cell carcinoma (RCC) is responsible for most cases of the kidney cancer. Previous research showed that low serum levels of cholesterol level positively correlate with poorer RCC-specific survival outcomes. However, the underlying mechanisms and functional significance of the role of cholestero...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104400/ https://www.ncbi.nlm.nih.gov/pubmed/33905408 http://dx.doi.org/10.1371/journal.pbio.3001197 |