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Reverse Remodeling in Human Heart Failure after Cardiac Resynchronization Therapy Is Associated With Reduced RHO-Kinase Activation

Background: Reverse remodeling is a clinically relevant endpoint in heart failure with reduced ejection fraction (HFrEF). Rho-kinase (ROCK) signaling cascade activation correlates with cardiac remodeling and left ventricular (LV) systolic dysfunction in HFrEF patients. Cardiac resynchronization ther...

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Detalles Bibliográficos
Autores principales:	Ocaranza, Maria Paz, Jalil, Jorge E., Altamirano, Rodrigo, de León, Ana, Moya, Jackeline, Lonis, Alejandra, Gabrielli, Luigi, Nab, Paul Mac, Córdova, Samuel, Paredes, Alejandro, Vergara, Ismael, Bittner, Alex, Sabat, Karime, Pastorini, Karla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104930/ https://www.ncbi.nlm.nih.gov/pubmed/33967744 http://dx.doi.org/10.3389/fphar.2021.565724

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