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SUMOylation of α-tubulin is a novel modification regulating microtubule dynamics
Microtubules (MTs) are regulated by a number of known posttranslational modifications (PTMs) on α/β-tubulin to fulfill diverse cellular functions. Here, we showed that SUMOylation is a novel PTM on α-tubulin in vivo and in vitro. The SUMOylation on α-tubulin mainly occurred at Lys 96 (K96), K166, an...
Autores principales: | Feng, Wenfeng, Liu, Rong, Xie, Xuan, Diao, Lei, Gao, Nannan, Cheng, Jinke, Zhang, Xu, Li, Yong, Bao, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104938/ https://www.ncbi.nlm.nih.gov/pubmed/33394042 http://dx.doi.org/10.1093/jmcb/mjaa076 |
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