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SUMOylation of α-tubulin is a novel modification regulating microtubule dynamics

Microtubules (MTs) are regulated by a number of known posttranslational modifications (PTMs) on α/β-tubulin to fulfill diverse cellular functions. Here, we showed that SUMOylation is a novel PTM on α-tubulin in vivo and in vitro. The SUMOylation on α-tubulin mainly occurred at Lys 96 (K96), K166, an...

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Detalles Bibliográficos
Autores principales: Feng, Wenfeng, Liu, Rong, Xie, Xuan, Diao, Lei, Gao, Nannan, Cheng, Jinke, Zhang, Xu, Li, Yong, Bao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104938/
https://www.ncbi.nlm.nih.gov/pubmed/33394042
http://dx.doi.org/10.1093/jmcb/mjaa076

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