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Robust and distributed neural representation of action values
Studies in rats, monkeys, and humans have found action-value signals in multiple regions of the brain. These findings suggest that action-value signals encoded in these brain structures bias choices toward higher expected rewards. However, previous estimates of action-value signals might have been i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104958/ https://www.ncbi.nlm.nih.gov/pubmed/33876728 http://dx.doi.org/10.7554/eLife.53045 |
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author | Shin, Eun Ju Jang, Yunsil Kim, Soyoun Kim, Hoseok Cai, Xinying Lee, Hyunjung Sul, Jung Hoon Lee, Sung-Hyun Chung, Yeonseung Lee, Daeyeol Jung, Min Whan |
author_facet | Shin, Eun Ju Jang, Yunsil Kim, Soyoun Kim, Hoseok Cai, Xinying Lee, Hyunjung Sul, Jung Hoon Lee, Sung-Hyun Chung, Yeonseung Lee, Daeyeol Jung, Min Whan |
author_sort | Shin, Eun Ju |
collection | PubMed |
description | Studies in rats, monkeys, and humans have found action-value signals in multiple regions of the brain. These findings suggest that action-value signals encoded in these brain structures bias choices toward higher expected rewards. However, previous estimates of action-value signals might have been inflated by serial correlations in neural activity and also by activity related to other decision variables. Here, we applied several statistical tests based on permutation and surrogate data to analyze neural activity recorded from the striatum, frontal cortex, and hippocampus. The results show that previously identified action-value signals in these brain areas cannot be entirely accounted for by concurrent serial correlations in neural activity and action value. We also found that neural activity related to action value is intermixed with signals related to other decision variables. Our findings provide strong evidence for broadly distributed neural signals related to action value throughout the brain. |
format | Online Article Text |
id | pubmed-8104958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-81049582021-05-11 Robust and distributed neural representation of action values Shin, Eun Ju Jang, Yunsil Kim, Soyoun Kim, Hoseok Cai, Xinying Lee, Hyunjung Sul, Jung Hoon Lee, Sung-Hyun Chung, Yeonseung Lee, Daeyeol Jung, Min Whan eLife Neuroscience Studies in rats, monkeys, and humans have found action-value signals in multiple regions of the brain. These findings suggest that action-value signals encoded in these brain structures bias choices toward higher expected rewards. However, previous estimates of action-value signals might have been inflated by serial correlations in neural activity and also by activity related to other decision variables. Here, we applied several statistical tests based on permutation and surrogate data to analyze neural activity recorded from the striatum, frontal cortex, and hippocampus. The results show that previously identified action-value signals in these brain areas cannot be entirely accounted for by concurrent serial correlations in neural activity and action value. We also found that neural activity related to action value is intermixed with signals related to other decision variables. Our findings provide strong evidence for broadly distributed neural signals related to action value throughout the brain. eLife Sciences Publications, Ltd 2021-04-20 /pmc/articles/PMC8104958/ /pubmed/33876728 http://dx.doi.org/10.7554/eLife.53045 Text en © 2021, Shin et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Shin, Eun Ju Jang, Yunsil Kim, Soyoun Kim, Hoseok Cai, Xinying Lee, Hyunjung Sul, Jung Hoon Lee, Sung-Hyun Chung, Yeonseung Lee, Daeyeol Jung, Min Whan Robust and distributed neural representation of action values |
title | Robust and distributed neural representation of action values |
title_full | Robust and distributed neural representation of action values |
title_fullStr | Robust and distributed neural representation of action values |
title_full_unstemmed | Robust and distributed neural representation of action values |
title_short | Robust and distributed neural representation of action values |
title_sort | robust and distributed neural representation of action values |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104958/ https://www.ncbi.nlm.nih.gov/pubmed/33876728 http://dx.doi.org/10.7554/eLife.53045 |
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