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CRISPR-based functional genomics in human dendritic cells

Dendritic cells (DCs) regulate processes ranging from antitumor and antiviral immunity to host-microbe communication at mucosal surfaces. It remains difficult, however, to genetically manipulate human DCs, limiting our ability to probe how DCs elicit specific immune responses. Here, we develop a CRI...

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Detalles Bibliográficos
Autores principales:	Jost, Marco, Jacobson, Amy N, Hussmann, Jeffrey A, Cirolia, Giana, Fischbach, Michael A, Weissman, Jonathan S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104964/ https://www.ncbi.nlm.nih.gov/pubmed/33904395 http://dx.doi.org/10.7554/eLife.65856

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