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The contact activation system and vascular factors as alternative targets for Alzheimer's disease therapy

Alzheimer's disease (AD) is the most common neurodegenerative disease, affecting millions of people worldwide. Extracellular beta‐amyloid (Aβ) plaques and neurofibrillary tau tangles are classical hallmarks of AD pathology and thus are the prime targets for AD therapeutics. However, approaches...

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Detalles Bibliográficos
Autores principales: Singh, Pradeep K., Badimon, Ana, Chen, Zu‐Lin, Strickland, Sidney, Norris, Erin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105157/
https://www.ncbi.nlm.nih.gov/pubmed/33977208
http://dx.doi.org/10.1002/rth2.12504