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Savolitinib ± Osimertinib in Japanese Patients with Advanced Solid Malignancies or EGFRm NSCLC: Ph1b TATTON Part C
BACKGROUND: Preliminary data suggest that combining savolitinib, a potent and highly selective MET-tyrosine kinase inhibitor (TKI), with osimertinib, a third-generation, irreversible, oral epidermal growth factor receptor-TKI (EGFR-TKI), may overcome MET-based resistance to EGFR-TKIs. OBJECTIVE: To...
Autores principales: | Yoh, Kiyotaka, Hirashima, Tomonori, Saka, Hideo, Kurata, Takayasu, Ohe, Yuichiro, Hida, Toyoaki, Mellemgaard, Anders, Verheijen, Remy B., Ou, Xiaoling, Ahmed, Ghada F., Hayama, Manabu, Sugibayashi, Ko, Oxnard, Geoffrey R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105224/ https://www.ncbi.nlm.nih.gov/pubmed/33939068 http://dx.doi.org/10.1007/s11523-021-00806-5 |
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