HIV-1 exposure promotes PKG1-mediated phosphorylation and degradation of stathmin to increase epithelial barrier permeability

Exposure of mucosal epithelial cells to the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 is known to disrupt epithelial cell junctions by impairing stathmin-mediated microtubule depolymerization. However, the pathological significance of this process and its underlying mol...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Wei, Chen, Mingzhen, Zhai, Zhaodong, Li, Hongjie, Song, Ting, Zhu, Yigao, Dong, Dan, Zhou, Peng, Duan, Liangwei, Zhang, You, Li, Dengwen, Liu, Xinqi, Zhou, Jun, Liu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105298/
https://www.ncbi.nlm.nih.gov/pubmed/33839152
http://dx.doi.org/10.1016/j.jbc.2021.100644

Ejemplares similares

Ejemplares similares