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ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss

Lipid metabolism-related gene mutations can cause retinitis pigmentosa, a currently untreatable blinding disease resulting from progressive neurodegeneration of the retina. Here, we demonstrated the influence of adiponectin receptor 1 (ADIPOR1) deficiency in retinal neurodegeneration using Adipor1 k...

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Detalles Bibliográficos
Autores principales: Osada, Hideto, Toda, Eriko, Homma, Kohei, Guzman, Naymel A., Nagai, Norihiro, Ogawa, Mamoru, Negishi, Kazuno, Arita, Makoto, Tsubota, Kazuo, Ozawa, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105316/
https://www.ncbi.nlm.nih.gov/pubmed/33963174
http://dx.doi.org/10.1038/s41419-021-03741-5