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Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex

Angiotensin converting enzyme 2 (ACE2) is a key regulator of the renin-angiotensin system, but also the functional receptor of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on structural similarity with other γ-secretase (γS) targets, we hypothesized that ACE2 may be affect...

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Detalles Bibliográficos
Autores principales:	Bartolomé, Alberto, Liang, Jiani, Wang, Pengfei, Ho, David D., Pajvani, Utpal B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105332/ https://www.ncbi.nlm.nih.gov/pubmed/33963249 http://dx.doi.org/10.1038/s41598-021-89379-x

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