The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2

Thyroid hormone receptor interactor 12 (TRIP12) is an E3 ligase most notably involved in the proteolytic degradation of the tumor suppressor p14ARF. Through this process, it is proposed that TRIP12 plays an oncogenic role in tumor initiation and growth. However, its role in other cancer processes is...

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Detalles Bibliográficos
Autores principales: Lee, Kwok Kin, Rajagopalan, Deepa, Bhatia, Shreshtha Sailesh, Tirado-Magallanes, Roberto, Chng, Wee Joo, Jha, Sudhakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105346/
https://www.ncbi.nlm.nih.gov/pubmed/33963176
http://dx.doi.org/10.1038/s41420-021-00479-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105346/
https://www.ncbi.nlm.nih.gov/pubmed/33963176
http://dx.doi.org/10.1038/s41420-021-00479-z

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