LINC-PINT impedes DNA repair and enhances radiotherapeutic response by targeting DNA-PKcs in nasopharyngeal cancer

Radioresistance continues to be the leading cause of recurrence and metastasis in nasopharyngeal cancer. Long noncoding RNAs are emerging as regulators of DNA damage and radioresistance. LINC-PINT was originally identified as a tumor suppressor in various cancers. In this study, LINC-PINT was signif...

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Detalles Bibliográficos
Autores principales: Wang, You-hong, Guo, Zhen, An, Liang, Zhou, Yong, Xu, Heng, Xiong, Jing, Liu, Zhao-qian, Chen, Xiao-ping, Zhou, Hong-hao, Li, Xiong, Liu, Tao, Huang, Wei-hua, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8105365/
https://www.ncbi.nlm.nih.gov/pubmed/33963177
http://dx.doi.org/10.1038/s41419-021-03728-2

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